In Methods in Pharmacology and Toxicology, Gurevich VV, Gurevich EV, Tesmer JJG (eds), pp 283299
Research has found that GLPs regulate the microbial communities inside the mouth, intestines, pancreas, and lungs of rats suffering from T2DM by significantly increasing abundance of beneficial bacteria such as * Lactobacillus *, * Bifidobacterium *, * Prevotella *, * Blautia *, selenium-rich bacteria, along with * Coprococcus *, in addition to by inhibiting harmful bacteria such as * Staphylococcus *, * Escherichia *, * Ruminococcus torques (Holdeman and Moore 1974)*, * Streptococcus mutans (Clarke 1924)*, and *Clostridium perfringens (Veillon and Zuber 1898) * , consequently bettering glucose metabolism disturbances and alleviating reduced sensitivity to insulin ( However, the gut microbiotas composition determines how intestinal barrier functionality and directly impacts progression of diminished response to insulin and obesity
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10.1074/jbc.M115.667063 241 WuD.ZhaoW.XuC.ZhouX.LengX.LiY