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There is no absolute contraindication to taking Wegovy and Wellbutrin together, though it should be noted that concurrent use represents an off-label prescribing decision that should follow careful clinical assessment and shared decision-making

According to the FDA prescribing label, reactions such as injection-site discomfort and erythema (redness) were reported in placebo-controlled trials

The mechanism is plausible, as B12 plays a role in neurological function that could influence nausea pathways, but it remains unproven

It can help you lose weight by reducing calorie intake, increasing energy expenditure, and improving your metabolism