Core Areas of In Vitro Investigation: Cellular Signaling Mechanics: Investigating how simultaneous receptor activation affects downstream biological markers
The further two-sample t -tests, also considering the FDR (Table S2 e S3), evidenced ten metabolites (3-hydroxybutyrate, isoleucine, alanine, valine, acetone, acetoacetate, leucine, lactate, phenylalanine, acetate) as significantly changed in the plasma, and three (acetoacetate, succinate and 3-hydroxybutyrate) in the pericardial fluid of IHD patients in comparison with controls, highlighted by the red dotted circle in VIP scores models in Fig
10.1007/BF00882764 24 NigelS
[24] [25] Individuals with MEN 2 carry germline RET mutations conferring near-100% lifetime risk of developing MTC, often presenting in childhood or early adulthood