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Edited by Dr Francesca Bernassola Rights and permissions Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made

2009 Jun Cara T Hoepner, Roger S McIntyre, George I Papakostas

Over many years, symptoms can worsen to the point of severe disability, necessitating placement in a skilled nursing facility (especially with the development of dementia or frequent falling)