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The growth hormone secretagogue receptor subtype 1a , is a Gq/11-coupled GPCR expressed at highest density in pituitary somatotroph cells and hypothalamic arcuate nucleus neurones, with peripheral expression in stomach, heart, liver, adipose tissue, and immune cells

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Moisture introduced at this stage can compromise the lyophilized peptide cake and accelerate degradation

(13)(14) Nevertheless, GHRP-2 appears to induce desensitization at these receptors immediately after exposure, potentially reducing sensitivity lasting a complete four hours before reversal