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When penta deca peptide arginate interacts with endothelial cells, it upregulates VEGFR2 expression at both the mRNA and protein levels

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The Billon 2025 paper (PMID 41421047) introduced SLU-PP-915 as an "orally active" sibling specifically because the parent SLU-PP-332 "lacks oral bioavailability." Despite that, the most common vendor formats are oral capsules and tablets products without published evidence that they produce systemic ERR agonism in humans