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On the other hand, TIMP-2 plays an opposite role to MMP-2 by inhibiting the protease activity in tissues undergoing remodeling of the ECM (Edelstein, 2017), thus a balance between MMP-2 and TIMP-2 plays a key role in maintaining the proper development and metabolism of the ECM

Collaboration between vitamin E isomers Although -tocopherol is the dominant form of vitamin E in the body, several studies have shown that other isomers, such as -tocopherol and -tocotrienol , enhance each other and can complement their actions

Faster-acting drugs have a higher abuse potential, DiFeliceantonio explained

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