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JAMA, 284 (7), 861868
Ub, ubiquitination
Rather, Yeungnam University, Republic of Korea Reviewed by Tahani Bakhsh, University of Jeddah, Saudi Arabia Laiba Arshad, Forman Christian College, Pakistan Updates Copyright 2023 Tian, Huang, Fu, Gao, Mi, Bai, Ma, Zhang, Lu, Zhao, Zhang, Jiang, Lin, Yue, Yuan and Meng
As ROS accumulate excessively, the mitochondrial outer membrane protein Tom20 and the Bax pathway are altered, leading to the release of cytochrome c and other pro-apoptotic/pro-pyroptotic molecules from mitochondria, thereby activating the downstream caspase cascade
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