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RGN-352 was shown to be safe and well-tolerated with no serious drug-related adverse events reported (PMID: 20536472) Phase 2 AMI trial (incomplete): RegeneRx designed a Phase 2 proof-of-concept trial (NCT01311518) to evaluate RGN-352 in approximately 75 patients with acute ST-segment elevation myocardial infarction (heart attack)

It concedes tirzepatide's numerical advantage in trial averages while arguing that potency on paper does not determine clinical success, because individual receptor sensitivity, tolerability and metabolic factors decide what actually happens

In May, Canada became the first country in the G7 to approve a generic semaglutide injection, intended for type 2 diabetes patients but can be prescribed off-label for weight loss

This is called off-label prescribing