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Phthalates disrupt ovarian steroidogenesis and have been associated with lower antral follicle counts and reduced IVF success rates. Cigarette smoke: Contains hundreds of toxicants including polycyclic aromatic hydrocarbons that accelerate follicular atresia (egg cell death) and directly damage oocyte DNA

The neurotrophic and neuroprotective effects of GLP-1 receptor (R) stimulation have been characterized in numerous in vitro and in vivo preclinical studies using GLP-1R agonists and dipeptidyl peptidase-4 inhibitors

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p21 CDK inhibitor, P 21 cyclin dependent kinase inhibitor