N Engl J Med 2019;381:84151
At baseline, 20.1% of the population reported retinopathy
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high doses may cause mild GI upset Monitor liver function if used long-term Common Side Effects Injection site reactions: pain, bruising, redness, swelling Mild nausea or stomach upset Headache Unusual taste in the mouth Mild fatigue after injection Temporary body odor changes (from high-dose choline) Seek Medical Attention For Signs of allergic reaction: rash, hives, swelling, difficulty breathing Severe injection site reaction or infection Unusual chest pain or heart palpitations References PT-141 / Bremelanotide (Compounded) PT-141, also known as bremelanotide, is a melanocortin receptor agonist that acts on the central nervous system to address hypoactive sexual desire disorder (HSDD)