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For individuals with Wilson's disease (a genetic disorder causing copper accumulation) or other copper metabolism disorders, theoretical caution is warranted, though even in these populations topical GHK-Cu is unlikely to pose significant risk given the minimal systemic absorption

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Additional indicators related to digitalisation show among others a higher potential exposure of occupations in the tourism sector towards Artificial Intelligence (Felten et al., 2021) and a relatively high share of digital skills needed to conduct their usual tasks (Lennon et al., 2023), even though such exposures are rather moderate when compared to their computerisation potentials

Portal and biliary phases of enterohepatic circulation of corrinoids in humans