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Meta-analysis was conducted using a random effects model where heterogeneity was low to moderate (I 2 = 0-60%)

Clinical Update 11/09/2019 Choline Concern A large study found that people with higher intakes of choline from their diets had a higher risk of death, specifically cardiovascular death, than people with lower choline intakes

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Medication Caution Bismuth subsalicylate may cause temporary, harmless blackening of stool and tongue