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Bydureon and Ozempic are glucagon-like peptide 1 (GLP-1) receptor agonists mainly known as diabetes medications meant for glycemic control improvement in patients with type 2 diabetes mellitus

Semaglutide also carries an FDA boxed warning: in rodent studies it caused thyroid C-cell tumors, and although the relevance to humans has not been established, it is contraindicated in anyone with a personal or family history of medullary thyroid carcinoma (MTC) or Multiple Endocrine Neoplasia syndrome type 2 (MEN 2)

Is Semaglutide effective on its own

Studies report that people using semaglutide lost about 1020% of body weight, while metformin users usually lost 25%