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Its role in preserving NAD+ and supporting mitochondrial health led to its use in advanced clinical longevity protocols as a tool to help protect NAD+

however, research has indicated that its efficacy was likely unrelated to ASCT2 inhibition, yielding again to the problem of non-specificity [108]

Due to its remarkable systemic healing properties in animal models, this compound has become a premier subject of study in the fields of musculoskeletal regeneration, angiogenesis, and gastrointestinal tissue repair

36 Glu1171Lys occurs in the sequence Gly-Asn-Arg-Gly-Glu-Arg, which does not appear to be an integrin binding site