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It has since been used in clinical settings for fatigue, muscle spasm, upper respiratory conditions, and immune support

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Baseline CRP 10 mg/L predicted higher odds of MELD-3 improvement, particularly in those with MELD-3 18, and decreases in CRP and NLR during follow-up were strongly associated with MELD-3 improvement, lower MELD, and substantially lower mortality

Conditions associated with variant 1298C include fibromyalgia, chronic fatigue, schizophrenia, chronic migraines, and irritable bowel syndrome