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When to Speak with a Clinician You should reach out to a provider if you notice persistent nausea after the first few weeks, strong bloating that does not improve, trouble passing stool for several days, repeated vomiting, sharp or severe abdominal pain, or if food seems to sit in your stomach for too long without moving

(145) demonstrated that peripherally administered liraglutide and semaglutide accessed ARH directly without crossing the blood-brain barrier