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A clinical trial found that participants taking 500 mg of oral glutathione daily showed decreased melanin indices at all six measured body sites after just 4 weeks

The agency held a Pharmacy Compounding Advisory Committee meeting on July 23-24, 2026 to take public comment and advise on compounded substances, which is the formal venue where this gets argued rather than assumed

This is especially relevant for RA patients who arent significantly overweight but still have metabolic inflammation insulin resistance, prediabetes, or a stubbornly elevated CRP despite adequate drug doses

These are not automatically appropriate for everyone, and natural does not always mean well-tolerated in highly sensitive patients, so clinical guidance matters