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Targeting polycystic ovary syndrome (PCOS) pathophysiology with flavonoids: from adipokine-cytokine crosstalk to insulin resistance and reproductive dysfunctions
Conclusion As the multi-hit hypothesis holds, combining the therapeutic approaches of GLP-1 agonists with resmetirom seems like a promising strategy by targeting the multifaceted pathophysiology of MASH, which may lead to improved patient outcomes
6a), in most of the diseases a correlation was observed
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