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Large-scale trials like the Women's Health Initiative (WHI) demonstrate that a 5% or greater weight loss is associated with a 12% reduction in obesity-associated cancers (HR, 0.88

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So, as dermatologists, we have to keep an eye out for new developing acne in patients on these medications, counsel our patients first and foremost and then be ready to treat the acne. Tolkachjov recommends that if an adult woman on a GLP-1 receptor agonist comes into the clinic reporting sudden acne, try to treat the acne with topicals first unless inflammatory or scarring acne is present, working up to isotretinoin if necessary