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Common scenarios include achieving target weight loss goals, experiencing intolerable adverse effects such as persistent nausea or gastrointestinal disturbances, financial constraints related to medication costs, pregnancy planning or confirmation (tirzepatide should be discontinued when pregnancy is recognized), or development of contraindications

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J Trace Elem Med Biol 46:7682 Gorini F, Muratori F, Morales MA (2014) The role of heavy metal pollution in neurobehavioral disorders: a focus on autism