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While tirzepatide does not directly target reproductive hormones, the significant weight loss and metabolic changes it produces can influence the hypothalamic-pituitary-ovarian axis that regulates menstruation

Tirzepatide: GI side effects common but well-characterized

Researchers have been exploring the use of positron emission tomography (PET) imaging to detect ghrelin receptor activity

Mitochondrial dysfunction has been recently proposed as a key pathophysiological mechanism [3] linked to processes commonly found in depression, including neurotoxicity, impaired neuroplasticity, inflammation and insulin resistance [2,3,4,5]