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Unlike previous reviews, this review emphasizes next-generation probiotics, live biotherapeutics, and genetically engineered microbes, and their synergistic interactions with dietary bioactives such as polyphenols and fibers

Gallbladder disease , including gallstones, has been reported with GLP-1 receptor agonists

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Multi-center trials with standardized protocols would help assess biomarkers, cognitive outcomes, and disease progression markers