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We estimated that with this sample size, the study would have 80% power to detect an absolute difference in the rate of improvement in ALT of 30 percentage points, with a two-sided type 1 error of 0.05

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Nutritional supplements and their effect on glucose control

The increased permeability described as what increased intestinal permeability means is a real phenomenon seen in certain conditions, even though "leaky gut syndrome" is not a formal stand-alone diagnosis