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The standard starting dose is 0.25 mg weekly
Patients with a history of eating disorders, seizures, uncontrolled hypertension, or current use of opioid medications should avoid Contrave due to contraindications and safety concerns
Moreover, by prioritizing FFA as the primary source of oxidation, SGLT2i signal an increased need for glucose to the cell
GLP-1 receptors are found in pancreatic beta cells, the gastrointestinal tract, areas of the brain involved in appetite regulation, and to some extent in cardiovascular, renal, and certain immune cells
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