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Discussion We report 3 probands from two unrelated families with rare BBOX1 variants, L-carnitine deficiency, and elevated levels of plasma -BB, indicative of a causative effect of the BBOX1 variants affecting the final stage of the L-carnitine biosynthetic pathway

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The Full TRIUMPH Clinical Programme TRIUMPH-1 is the headline trial, but Eli Lillys retatrutide programme spans multiple Phase 3 studies covering different patient populations and indications