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Ethics declarations Declarations Ethical approval Ethical permissions from the Research Ethical Committee at the Faculty of Medicine, Menoufia University, Egypt with IRB No 12/2023 BIO-6 were obtained

Although oxidative stress was defined originally as a balance between oxidants and antioxidants systems, an equilibrium among antioxidant strategies is needed to avoid the generation of oxidants and ROS (Mari et al., 2010)

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6c) that can be phosphorylated 8,20 , so we next asked whether P-Thr358 and P-Thr369 are essential for SNIP1 binding or whether they can be substituted by the remaining P-Thr