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Facilitates an immune system response: Glutathione facilitates an immune system response by regulating the production of cytokines, which are signaling molecules that mediate inflammation

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In response to oxidative stress, neurons undergo overactivation of the enzyme poly (ADP-ribose) polymerase-1 (PARP1) to prevent DNA damage, which decreases intracellular NAD and ATP levels, compromising the efficiency of glycolysis and oxidative phosphorylation, affecting the ability of neurons to generate ATP (200, 203)