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RNA sequencing analyses have confirmed GLP-1R gene expression in EAT, and immunofluorescence studies have further validated the presence of GLP-1R protein, whereas no such signal has been detected in subcutaneous fat (95)

No study has systematically examined whether iron overload drives senescence and fibrosis, or if senescence worsens iron retention and chronic inflammation

In studies focused on obesity management, Retatrutide is often initiated at a low dose, such as 1 mg or 2 mg per week, to minimize potential side effects like nausea or gastrointestinal discomfort

How gastric ultrasound helps What is gastric ultrasound (GUS)