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In 1967, Luzzatto 12 postulated at least two sites of union of the NADP to the enzyme, with a condition of transition from low to high affinity when NADPs concentration increases, which means that there exist two possible forms of the enzyme, according to its affinity by the NADP

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Accordingly, total clearance of SARS-CoV-2 RNA or its protein antigens from host infected tissue may take a longer time, while the virus and its antigenic fragments continue to remain dormant for extended periods of time in the body

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