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Regular blood tests to monitor clotting parameters may be necessary to avoid bleeding complications

This fingerprint should link molecular signatures (e.g., co-expression of ACSL4 and 4-HNE) to histological lesions (e.g., tubular necrosis and fibrosis), enabling precise localization and quantification of ferroptosis in the renal microenvironment

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For the cell-based liver models, we calculated both sensitivity and specificity for detection of both carcinogenic and in vitro/in vivo mutagenic NAs, based on the outcomes for NAs with available carcinogenicity and in vitro/in vivo mutagenicity data