Application protocol: Product: Hydrocortisone 1% cream (available at any pharmacy without prescription) Timing: Apply after noticing the reaction, not before injection Amount: Thin layer covering the entire affected area plus a 1-centimeter margin Frequency: Twice daily (morning and evening) until the reaction resolves Duration: Typically 2 to 5 days, do not use for more than 7 consecutive days without medical guidance Important: Do NOT apply hydrocortisone before injection, as it can interfere with medication absorption For reactions that do not respond to 1% hydrocortisone, a healthcare provider can prescribe stronger topical corticosteroids (triamcinolone 0.1% or betamethasone 0.05%)
Among these, 183 trials were registered on ClinicalTrial.gov, 56 were identified from other trial registries such as the ICTRP and Australian New Zealand Clinical Trials Registry (ANZCTR), and 23 were standalone publications not linked to any available registration
As with any change to your health regimen, consult with a healthcare professional if you have specific medical concerns
Y., Zhang, J., Wang, L., Zhao, S., Che, Y