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Body weight and fasting plasma glucose were measured at before breakfast and dosing at baseline and end-of-treatment

When we don't get enough vitamin B12, it can: Reduce ATP production, potentially contributing to mitochondrial dysfunction and insulin resistance Cause megaloblastic anemia, characterized by abnormally large, hemoglobin-poor red blood cells that die prematurely

the choice depends on convenience and individual tolerance

3.4 Network meta-analysis of DPP-4i, GLP-1 RAs, and SGLT-2i on total fracture risks The network meta-analysis had been performed via random effects model including 13 population-based cohort studies giving the odds ratio of total bone fractures associated with each treatment in comparison to other glucose-lowering medications shown in ( Figure 2 )