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In monotremes it is the same Gcg gene encoding GLP-1 that is expressed in gut and venom

A cost comparison of GLP-1 receptor agonists and bariatric surgery

doi:10.1677/joe.0.1380159 Baggio LL, Drucker DJ

The blunted effect of glucose-dependent insulinotropic polypeptide in subcutaneous abdominal adipose tissue in obese subjects is partly reversed by weight loss