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TNFR2 activation induces phosphatidylinositol 3-kinase (PI3K)-mediated protein kinase PKB/Akt phosphorylation by an unknown mechanism [107, 108]

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The AOD designation stands for Anti-Obesity Drug, reflecting the original research objective when the compound was developed by scientists at Metabolic Pharmaceuticals in the 1990s

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Callaghan BC, Little AA, Feldman EL, et al

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