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Expansion of adipose tissue increases expression of 11-hydroxysteroid dehydrogenase type 1 (11-HSD1), which converts inactive cortisone to active cortisol, thereby amplifying cortisol exposure in local tissues [82, 83]

This prevents bacterial growth, making it suitable for multi-dose applications and safe for mixing or diluting injectable medications

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Published in Journal of Proteome Research 2016 Dec 2;15(12):4579-4590