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Oversight in 2025 shows that the agency is watching the GLP-1 space (diabetes, obesity, weight loss drugs) particularly closely, compounded versions or unverified imports will face tough regulatory headwinds

In one study, among patients with non-small cell lung cancer treated with anti-PD-1/PD-L1, those who received corticosteroids to manage their irAE had reduced clinical benefit from immunotherapy, with shorter progression-free survival and overall survival

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It is particularly relevant for patients whose training produces diffuse connective tissue stress across multiple joints simultaneously, which is common in athletes running compound movements at high volumes