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Various dual/triple agonists for glucagon-like peptide-1 receptor (GLP-1R), which also target the gastric inhibitory peptide receptor and glucagon receptor, have recently been explored to increase treatment efficacy for both diabetes and obesity in the clinical setting [9, 10]

Triple agonismo GLP-1, GIP y glucagn en el manejo cardiometablico El programa clnico de retatrutide, desarrollado por Eli Lilly and Company, representa una nueva generacin de terapias cardiometablicas basadas en triple agonismo (GLP-1, GIP y glucagn)