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GIP Receptor Distribution: **Adipose tissue: Adipocyte metabolism, nutrient partitioning Brain: Modulates energy balance Bone: May positively influence bone metabolism Clinically, this translates into greater weight loss than GLP-1 aloneoften approaching or exceeding 20% of body weight in trials

Compounding is meant to be used only in narrow circumstances, such as during an official drug shortage or when a patient cannot take a branded medication for specific medical reasons

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for instance, there is an enhanced propensity for carbohydrate intake in hyperinsulinemic hypoglycemic patients [64]