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Third, immortal time bias may artificially inflate apparent protective effects if the period between cohort entry and treatment initiation is misclassified as exposed time

Existing evidence on GLP-1s for smoking cessation is reviewed in our comprehensive, and regularly updated, article, GLP-1 for Addiction: the Medical Evidence for Opioid, Nicotine, and Alcohol Use Disorder

This may seem obvious, but it is critical to understand that if the physician, APRN or PA has never met or interacted with the person in a sufficient way, they cant prescribe them treatments or medication

10.1165/rcmb.2007-0025OC 89 HoffmannD