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Metformin attenuates renal tubulointerstitial fibrosis via upgrading autophagy in the early stage of diabetic nephropathy

Consequently, while the reductionist classical view might be valid for describing ordinary solution chemistry performed in laboratory glassware (the surrounding solvent acting as a heat bath for the reactants), it is inadequate when considering protein structure and function within the cellular cytoplasm: for there is nothing random, chaotic, or statistical about cellular biochemical events

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10.1002/hep.30556 Hepatology 109 Remsing RixL