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Thus, GSH participates as a co-factor in several reactions, including the elimination of peroxides by GSH peroxidases (GPx), the covalent addition to protein cysteines (Protein-SSG) predominantly performed by glutaredoxin, and the detoxification of electrophiles by S-glutathionylation (GS-R) formation as catalyzed by the enzymes glutaredoxin and glutathione S-transferase (GST) [4,11,12]

Methylcobalamin and adenosylcobalamin are two forms that are active in human metabolism

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However, lower levels of ROS can be advantageous and are implicated in a variety of signaling pathways