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A 42-year-old female with longstanding profound fatigue, chronic pain, asthma, multiple food intolerances, GI symptoms including diarrhea, urticaria, food cravings, weight gain, and migraine who was essentially housebound due to constant exhaustion (she estimated 30% of normal energy) took tirzepitide at 3.75 mg principally to address obesity

Seven days after transfer, T cells expressing the fusion protein had reduced DDR proteins at telomeres and increased IFN, TNF, and IL-2 production, compared to controls

Without adequate blood supply, all the collagen-stimulating peptides in the world won't help

PtdIns3P controls mTORC1 signaling through lysosomal positioning