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Furthermore, mitochondrial dysfunction promotes NLRP3 inflammasome assembly and caspase-1 activation, leading to the secretion of pro-inflammatory cytokines like IL-1, which are associated with the aberrant activation of CDK5 [53, 54]

The fluorescence was analyzed by flow cytometry (Attune NxT, ThermoFisher Scientific)

First isolated from human plasma, GHK-Cu is one of the most extensively studied peptides in published research literature, frequently referenced in models exploring skin biology, collagen and elastin signalling, gene expression modulation, and extracellular matrix remodelling pathways

Dietary supplements should not be used as a substitute for a varied diet