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TMAO has been proven to aggravate CVD by promoting atherosclerosis and thrombotic risk and has also been reported to be correlated with other cardiometabolic diseases such as non-alcoholic fatty liver disease and chronic renal disease [6,7,8]

Potential downsides include a slower onset of significant weight loss compared to tirzepatide and gastrointestinal side effects, particularly nausea during the first month, that can be challenging when you are already dealing with fatigue and disrupted eating patterns

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