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Histopathology and immunohistochemistry of pancreatic islets in fibrocalculous pancreatic diabetes

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The injection of CagA leads to aberrant cellular signaling, including interactions with Src homology 2 (SH2) domain-containing protein tyrosine phosphatase 2 (SHP2) and phosphoinositide 3-kinase (PI3K), driving the transformation of normal epithelial cells into neoplastic ones (173)

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