Journal of Toxicology, 2021 , 8871526
Dysfunction within the CNS Brain imaging studies have demonstrated an association between PDPN and structural changes in key somatosensory regions, such as the thalamus and somatosensory cortex, and altered functional connectivity within ascending pain pathways and cortical regions involved in pain processing
Endothelium xanthine dehydrogenase interacts with xanthine oxidase (XO) producing O and H 2 O 2 , and thus, generating another source of free radicals (Turrens, 2003) (Figure 1)
One reason for this is that the weights are much heavier, and the final repetition is to fatigue. To clarify, you cannot budge the weight for the last rep you do, and you feel the burn. There is good, quality research on the efficacy of the super slow protocol