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Symptomatic awareness of hypoglycemia may be less pronounced in patients with longstanding diabetes, in patients with diabetic neuropathy, using drugs that block the sympathetic nervous system (e.g., beta-blockers) [see Drug Interactions (7)], or who experience recurrent hypoglycemia

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Lowering the risk of Parkinsons disease with GLP-1 agonists and DPP4 inhibitors in type 2 diabetes

FDA-approved brand-name GLP-1 medications carry significant retail price tags, and insurance coverage varies widely