DMSO can easily pass through a biological membrane without permanently changing its structure, because of its hydrogen-bonding behavior, water affinity, ability to interchange with water in membranes, and ability to react with organic molecules [16,17]
doi: 10.3389/fonc.2020.571127 46 TangRHuaJXuJLiangCMengQLiuJet al
Moreover, neurexins, key molecules involved in the regulation of synaptic plasticity, act as critical links between synaptic plasticity and sustained antidepressant effects, involving mechanisms including protein level, selective splicing, epigenetics, astrocytes, positional redistribution and protein structure
This has led many people to explore compounded semaglutide