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First-line treatment typically involves: Methotrexate the most commonly prescribed conventional synthetic DMARD Sulfasalazine or hydroxychloroquine alternative or combination options Leflunomide for patients who cannot tolerate methotrexate These medications are usually combined with short-term corticosteroids (such as prednisolone) to provide rapid symptom relief whilst DMARDs take effect, which can take several weeks to months

Follow professional guidance for a balanced, sustainable approach to better sleep and recovery

Gastroenterology 154 , 20682086 (2018)

Pass/fail determination: Whether each test met specifications